The lifespan extension from senolytic drugs in aged mice did not come at the cost of a prolonged period of frailty at the end of life; deaths from age-related diseases occurred later.
Notes on verification
Confirmed by peer-reviewed primary source (Xu et al., Nature Medicine 2018) and corroborated by NIH, ScienceDaily, and GEN news coverage, all consistent with no contradicting evidence found. [cascade flags: aggregator_dropped_primary_exists | tier=silver indep_score=0.925 clusters=2 claim_tier=notable]
Sources
- Los senolíticos mejoran la salud y prolongan la vida: resultados del ... (seed:health_and_medicine)
- https://pmc.ncbi.nlm.nih.gov/articles/PMC6082705/ (corroboration)
- https://www.nih.gov/news-events/news-releases/senolytic-drugs-reverse-damage-caused-senescent-cells-mice (corroboration)
- https://www.genengnews.com/topics/drug-discovery/lifespan-extended-health-improved-by-senolytic-drugs/ (corroboration)