Researchers described the period 5-36 months past menopause as the 'critical window' of rapid estrogen depletion.
Notes on verification
Confirmed by multiple sources reporting on the same 2016 Mayo Clinic/KEEPS study press release; specific figure consistently reproduced across independent outlets, though ultimately traced to one original source. [cascade flags: aggregator_dropped_primary_exists | tier=unverified indep_score=0.3 clusters=4 claim_tier=notable] [rescored 2026-09-15: curated origin-host map (PR #65); unclassified hosts no longer scored as aggregators]
Sources
- Estrogen Patch in Newly Postmenopausal Women May Reduce ... (seed:health_and_medicine)
- https://www.newswise.com/articles/estrogen-patch-in-newly-postmenopausal-women-may-reduce-alzheimer-s-risk (corroboration)
- https://neurosciencenews.com/estrogen-alzheimers-menopause-4669/ (corroboration)
- https://womensbrainhealth.org/think-tank/think-twice/estrogen-patch-in-newly-postmenopausal-women-may-reduce-alzheimers-risk (corroboration)
- https://www.techtimes.com/articles/169569/20160713/estrogen-patches-may-reduce-alzheimers-risk-in-postmenopausal-women.htm (corroboration)