ScienceContemporaryglobalhigh confidence

People with endometriosis have higher rates of other immune-mediated conditions such as lupus, multiple sclerosis, and inflammatory bowel disease.

Notes on verification

Multiple independent peer-reviewed sources (systematic review/meta-analysis, large case-control study, and genetic study) consistently confirm increased rates of autoimmune/immune-mediated conditions in endometriosis patients, though causal mechanisms and genetic correlations remain debated and evidence quality for specific disease pairs varies. [tier=gold indep_score=1.0 clusters=5 claim_tier=notable | framework convergence=partial (upstreams: Shigesi et al. 2019 systematic review and meta-analysis (Human Reproduction Update), Eaton et al. 2007 Danish National Patient Register study, Aziz et al. 2025 case-control study (npj Women's Health), UK Biobank genetic study (Oxford, 2025)) — publishers independent, evidence may not be | kind=empirical eligibility=high (extractor: attributed/medium)]

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