Science2010sUnited Stateshigh confidence

In the Mayo Clinic study of 68 women, 21 received estrogen through a skin patch, 17 received estrogen orally, and 30 received a placebo.

Notes on verification

Confirmed by Mayo Clinic press release and independent peer-reviewed PubMed abstract with matching group sizes (21 transdermal, 30 placebo, 17 oral = 68 total). Cross-verified by an independent science news outlet as well. [tier=silver indep_score=0.925 clusters=2 claim_tier=notable]

Sources