In the Di Francesco et al. (2024) study of female mice, the lifespan-extension effect was largest with 40% chronic caloric restriction, followed in order by 20% chronic caloric restriction, 2-day intermittent fasting, and 1-day intermittent fasting.
Notes on verification
Directly confirmed by the primary Nature publication and its preprint, with consistent corroboration from secondary summaries and an institutional repository. [tier=gold indep_score=0.925 clusters=4 claim_tier=notable]
Sources
- Life-extending interventions do not necessarily result in ... - PMC (seed:health_and_medicine)
- https://www.nature.com/articles/s41586-024-08026-3 (corroboration)
- https://www.biorxiv.org/content/10.1101/2023.11.28.568901.full.pdf (corroboration)
- https://www.news-medical.net/news/20241022/Caloric-restriction-extends-mouse-lifespan-and-health-in-new-genetic-study.aspx (corroboration)
- https://mouseion.jax.org/stfb2024/260/ (corroboration)