Science2010sUnited Stateshigh confidence

Among patients receiving long-term opioid prescriptions exceeding 90 days, the adjusted odds ratio for a new opioid use disorder diagnosis was 15 at 1–36 MME/day, 29 at 36–120 MME/day, and 122 at ≥120 MME/day, compared with no opioid prescription.

Notes on verification

Confirmed by two independent sources: a secondary CDC guideline analysis and the original peer-reviewed Edlund et al. study, with matching adjusted odds ratios (15, 29, 122) for chronic opioid use by dose category. [tier=silver indep_score=0.925 clusters=2 claim_tier=notable]

Sources

Among patients receiving long-term opioid prescriptions e… · DeepInquiry