Among commercially insured patients with a previous opioid overdose, repeated overdose within 2 years occurred in 17% of those prescribed 100 MME/day or more, 15% of those prescribed 50–100 MME/day, 9% of those prescribed less than 50 MME/day, and 8% of those prescribed no opioids.
Notes on verification
Exact figures corroborated by original study abstract (Larochelle et al., Ann Intern Med, 2016) and independently confirmed by a Kaiser Permanente clinical guideline citing the same data. [tier=unverified indep_score=0.3 clusters=2 claim_tier=notable] [rescored 2026-09-15: curated origin-host map (PR #65); unclassified hosts no longer scored as aggregators]
Sources
- CDC Clinical Practice Guideline for Prescribing Opioids for Pain (seed:health_and_medicine)
- https://www.uptodate.com/contents/prescription-drug-misuse-epidemiology-prevention-identification-and-management/abstract/46 (corroboration)
- https://wa.kaiserpermanente.org/static/pdf/public/guidelines/opioid.pdf (corroboration)