A 1998 study published in Nature Medicine found that mice lacking neutrophil elastase show impaired host defense against gram-negative bacterial sepsis.
Notes on verification
Confirmed via PubMed (PMID 9585234) and Nature Medicine journal listing; matches title, journal, year, and findings exactly. [tier=silver indep_score=1.0 clusters=2 claim_tier=notable]
Sources
- Structures of Neutrophil Serine Protease 4 Reveal an Unusual ... (seed:psychology_and_neuroscience)
- https://pubmed.ncbi.nlm.nih.gov/9585234/ (corroboration)
- https://www.nature.com/articles/nm0598-615 (corroboration)